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Cover of Methotrexate: (English)

Methotrexate: (English)

(Paperback)

Jesse Russell, Ronald Cohn,

Book on Demand Ltd. (Publisher)

Published
2013
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High Quality Content by WIKIPEDIA articles! Methotrexate (rINN) ( /mɛθɵˈtrɛkseɪt/), abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid. Methotrexate began to replace the more toxic antifolate aminopterin starting in the 1950s. The drug was developed by Yellapragada Subbarao.

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